ECO-FRIENDLY SYNTHESIS OF NICKEL NANOPARTICLES USING ALOE VERA LEAF EXTRACT AND EVALUATION OF THEIR ANTIOXIDANT ACTIVITY

Authors

  • Ramarao Gollapalli Faculty of Pharmacy, Lincoln University College, Malaysia Author
  • K. Suresh babu Faculty of Pharmacy, Lincoln University College, Malaysia Author

DOI:

https://doi.org/10.61841/nn-pbs-12-1-7

Keywords:

Nickel nanoparticles (NiNPs), Aloe vera leaf extract, Antioxidant activity, Eco-friendly method

Abstract

In this study, researcher analyse the antioxidant properties and physicochemical characterisation of nickel nanoparticles (NiNPs) synthesised using Aloe vera leaf extract in an environmentally friendly manner. Plant-mediated green synthesis is an excellent alternative to standard chemical methods that address the growing need for environmentally friendly and non-hazardous synthesis methods. Aloe vera bioactive compounds such phenolics, flavonoids, and polysaccharides stabilise and decrease nanoparticle production. These properties are necessary for nanoparticle growth.

The reaction mixture changed colour, indicating that nickel ions (Ni2+) were reduced into nanoparticles. This experiment was performed using an aqueous aloe vera leaf extract. Many analytical approaches were utilised to characterise the synthesised NiNPs. UV-Visible spectroscopy was utilised to study nanoparticle absorption to validate their formation. Raman spectroscopy illuminated structural and molecular connections. To understand nickel nanoparticle electrical properties and polarisation, dielectric experiments were performed. X-ray diffraction (XRD) was also used to confirm the nanoparticles' crystalline nature and cleanliness. The antioxidant activity of the NiNPs was tested in vitro using standard procedures. The DPPH radical scavenging and FRAP assays were used. Adding phytochemicals from aloe vera to nanoparticles improves their free radical-scavenging ability. The findings show that nanoparticles have high nanoscale antioxidant potential. This study shows that generating nickel nanoparticles using aloe vera leaf extract is simple, cost-effective, and environmentally friendly. Synthesised NiNPs may be used in nanotechnology, biology, and medicines. NiNPs are well-characterised and have high antioxidant action.

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Published

2026-04-21

How to Cite

ECO-FRIENDLY SYNTHESIS OF NICKEL NANOPARTICLES USING ALOE VERA LEAF EXTRACT AND EVALUATION OF THEIR ANTIOXIDANT ACTIVITY (R. Gollapalli & K. S. babu, Trans.). (2026). Journal of Advance Research in Pharmacy and Biological Science (ISSN 2208-2360), 12(2), 1-10. https://doi.org/10.61841/nn-pbs-12-1-7